[Cite as http://purl.org/au-research/grants/nhmrc/570995]
A/Pr Beric Henderson
Brief description Inherited gene mutations that cause colon cancer kill 4,700 Australians every year. About 1 in 21 Australians develop colorectal cancer by age 75. Activation of the beta-catenin protein is a critical switch in the path to colon cancer. We discovered that beta-catenin, and another protein it interacts with called IQGAP1, move between different cellular compartments. We plan to study this process in more detail, as it relates to how beta-catenin works and to understanding its role in cancer.
Funding Amount $AUD 511,703.14
Funding Scheme NHMRC Project Grants
Standard Project Grant