grant

Reappraisal of the mechanisms underlying implantation success or failure [ 2018 - ]

Also known as: 5011621

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1139489]

Researchers: Prof Lois Salamonsen (Principal investigator) ,  Dr David Greening Dr Jemma Evans Dr Sally Catt Prof Beverley Vollenhoven
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Brief description Infertility affects 1:6 Australian couples; these seek help. However, for each IVF cycle, there is only ~18.5% chance of a live birth, significantly due to failure of embryo implantation. We discovered nano-vesicles in the uterine cavity, that are released from the womb lining and taken up by the pre-implantation embryo to improve its implantation potential. We will determine how this extracellular environment can enhance implantation success and circumvent/management of infertility.

Funding Amount $750,755.00

Funding Scheme Project Grants

Notes Standard Project Grant

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