A randomised trial of zoledronic acid for osteoarthritis of the knee [ 2013 - 2017 ]

Research Grant

Researchers: Prof Graeme Jones (Principal investigator) ,  Dr Dawn Aitken ,  Prof Catherine Hill ,  Prof Flavia Cicuttini ,  Prof Lyn March

Brief description Osteoarthritis (OA) is the most common form of arthritis and is increasing markedly due to an ageing population. Despite its large disease burden, there are currently no approved disease-modifying drugs available which modify structural progression of OA. The aim of this study is to compare zoledronic acid treatment to placebo on knee structural change and knee pain over two years. It is hypothesised that zoledronic acid will reduce cartilage loss, knee pain, and bone marrow lesion size.

Funding Amount $AUD 989,238.08

Funding Scheme Project Grants

Notes Standard Project Grant