grant

A Randomised controlled trial of high dose folic acid to slow the progression of atheroma in renal failure (194246) [ 2002 - 2004 ]

Also known as: Study of folic acid supplementation in kidney failure patients to reduce heart disease

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/194246]

Researchers: Prof Barry Mcgrath (Principal investigator) ,  Dr Pauline Branley Prof Peter Kerr Prof Robert Atkins

Brief description The Atherosclerosis and Folic Acid Supplementation Trial (ASFAST) is examining the effect of high dose folic acid supplementation on the development of desease of the heart and blood vessels in people with kidney failure. Subjects in the study take 15mg folic acid daily or a dummy tablet for 3 to 5 years. Folic acid is known to reduce the levels of a substance called homocysteine which is elevated in people with kidney disease. Homocysteine has been associated with disease of the heart and blood vessels and these diseases occur very commonly in people who also have kidney failure. I t is hoped that by using folic acid to reduce the levels of homocysteine, we can reduced the amounbt of heart and blood vessel disease in people with kidney failure.

Funding Amount $AUD 326,980.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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