Protecting the endothelial glycocalyx to improve transplant rates and outcomes [ 2016 - ]

Research Grant

Researchers: Prof Daniel Chambers (Principal investigator) ,  A/Pr Peter Hopkins ,  Dr Nicole Isbel ,  Dr Stephanie Yerkovich ,  Dr Timothy Sladden

Brief description A tiny, previously overlooked, structure called the endothelial glycocalyx (EG) is now known to ‘waterproof’ blood vessels. This grant extends our exciting preliminary data in the field of lung transplantation, where we have shown that EG loss is the main cause of a poorly functioning organ, to develop new tests of lung and kidney function, as well as treatments to resuscitate marginal organs outside the body, so improving access to and the safety of transplantation.

Funding Amount $725,180.00

Funding Scheme Project Grants

Notes Standard Project Grant