grant

Production and application of novel diagnostic and therapeutic reagents using transgenic mice [ 2002-01-01 - 2004-12-31 ]

Research Grant

[Cite as https://purl.org/au-research/grants/arc/LP0211022]

Researchers: Emeritus Professor Ross Barnard (Chief Investigator) ,  Dr Graeme Barnett (Partner Investigator)

Brief description Production and application of novel diagnostic and therapeutic reagents using transgenic mice. The project will be a collaboration between the University of Queensland and PanBio Ltd. We intend to use humanized transgenic mice to produce fully human monoclonal antibodies. Fully human antibodies have great advantages over murine antibodies as diagnostics and therapeutics. These reagents will be used to 1)replace human sera , 2)replace antigens from infectious organisms in a range of diagnostic kits for animal and human infectious disease and 3) as therapeutic leads and 4)to discover vaccine leads. The project will allow production of diagnostic kits where this was previously not feasible or not economically viable (eg. uncommon and/or dangerous animal or human diseases) and will lead to development of novel infectious disease diagnostics and therapeutics.

Funding Amount $194,344

Funding Scheme Linkage Projects

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Identifiers
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ACN 633 798 857