Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion Injury [ 2019 - ]

Research Grant

Researchers: Prof Jonathan Baell (Principal investigator) ,  Dr Chengxue Qin ,  Dr Girdhar Deora ,  Prof Carl Kirkpatrick ,  Prof Gemma Figtree
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Brief description The leading cause of death worldwide, accounting for 30% of all global deaths, is cardiovascular disease. This figure has heart attack and associated changes heart oxygen levels as a major injury-causing component. We have discovered a potential treatment that is limited by its solubility properties. In this R&D plan we will develop soluble preclinical progression drug candidates for the treatment of oxygen-related heart attack injury.

Funding Amount $677,127.00

Funding Scheme Development Grants

Notes Development Grant