grant

Preserving barriers: how cadherin signaling coordinates dynamic adhesion and tight junction assembly in epithelial cell. [ 2008 - 2010 ]

Also known as: Preserving epithelial cell-cell barriers.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/511156]

Researchers: Prof Alpha Yap (Principal investigator)

Brief description Epithelia protect the body from its environment. Breakdown of the epithelial barrier in tissues such as the skin and intestine, as occurs in burns and inflammation, leads to invasion of bacteria and severe metabolic disturbances. In this project we study the cell signaling mechanisms that maintain epithelial barriers in healthy tissues that undergo turnover and remodelling. Understanding these signaling pathways provides a foundation to understand how they are perturbed in disease.

Funding Amount $AUD 557,939.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857