grant

Preclinical relaxin therapy to reverse cardiac fibrosis and gain functional benefits [ 2015 - 2018 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1081710]

Researchers: A/Pr Xiao-Jun Du (Principal investigator)

Brief description Cardiac fibrosis is a key factor promoting heart disease and onset of complications including arrhythmias and heart failure. There is urgent and unmet need of drugs that can reverse fibrosis. By documenting anti-fibrotic action of a peptide hormone relaxin, CIA and his team will test therapeutic effect of relaxin in heart disease models focusing on fibrosis-reversal and functional gain, particularly arrhythmias. This work would promote development of relaxin as a new cardiovascular drug.

Funding Amount $AUD 724,754.67

Funding Scheme Project Grants

Notes Standard Project Grant

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