grant

A preclinical model of relapse in acute lymphoblastic leukaemia [ 2008 - 2010 ]

Also known as: A study of the mechanisms leading to drug-resistance and therapy failure in childhood leukaemia

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/513765]

Researchers: Prof Ursula Kees (Principal investigator) ,  Dr Alex Beesley Prof Richard Lock

Brief description Leukaemia is the most common type of cancer in children but resistance to therapy continues to be a significant problem. This project will investigate the biology of drug-resistance and relapse using a mouse model that replicates the human disease. We hope to identify novel therapeutic targets that can be used in combination with existing therapies to improve outcomes in this disease. We also hope to identify markers that can be used to screen for patients at increased risk of relapse.

Funding Amount $AUD 573,515.25

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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