Preclinical development of TLR signalling inhibitors for prevention of preterm labour and fetal inflammatory injury [ 2018 - 2020 ]

Research Grant

Researchers: Prof Sarah Robertson (Principal investigator) ,  Prof Jeffrey Keelan ,  Prof Mark Hutchinson

Brief description Preterm birth affects 8% of Australian births and is a major cause of infant and child health problems. Therapies to prevent or delay prematurity are urgently required. This study will investigate new drugs that suppress the triggers of preterm labour. We will evaluate drug effects in mice and human placental tissue, to demonstrate safety and fetal protection from inflammatory injury that occurs with prematurity. Successful completion of the study is expected to lead to clinical trials in women.

Funding Amount $AUD 700,492.50

Funding Scheme Project Grants

Notes Standard Project Grant