Potent Small Molecule Modulators of a Complement Protein In Inflammation [ 2018 - 2020 ]

Research Grant

Researchers: Prof David Fairlie (Principal investigator) ,  Dr Abishek Iyer

Brief description We have invented powerful new compounds that act on the cell surface and regulate inflammation. We plan to (1) fine-tune our small molecules for optimal activity on different kinds of immune cells; (2) understand mechanisms by which the compounds affect cellular inflammatory responses; (3) evaluate the compounds as potential treatments in rodent models of inflammatory diseases implicated from cell studies. This study is anticipated to lead to clinical studies for a new kind of drug treatment.

Funding Amount $AUD 699,079.98

Funding Scheme Project Grants

Notes Standard Project Grant