Postnatal germ cells are controlled by FSH during 'minipuberty' at 3-6 months, and deranged by cryptorchidism to cause seminoma and infertility [ 2017 - ]

Research Grant

Researchers: Prof John Hutson (Principal investigator) ,  Dr Bridget Southwell ,  Dr Ruili Li ,  Prof Joergen Thorup

Brief description This study will investigate the exciting possibility that the risk of cancer and infertility in adulthood in infants born with undescended testes might be obviated by understanding how primitive sperm cells behave in the postnatal testis. The study will define the key changes to the primitive sperm cells, including their timing and control by hormones, so surgery is done at the right time +/-accessory hormone treatment to optimise future sperm function for babies with undescended testes.

Funding Amount $813,739.00

Funding Scheme Project Grants

Notes Standard Project Grant