Post-translational control of indoleamine 2,3-dioxygenase [ 2009 - 2013 ]

Research Grant

Researchers: A/Pr Shane Thomas (Principal investigator) ,  Prof Nicholas King

Brief description It is apparent that a protein called indoleamine 2,3-dioxygenase is important for controlling the immune system of relevance to various normal and disease conditions including pregnancy, cancer, inflammation, infectious disease and autoimmunity. Despite this little is known about how this important protein is controlled. The aim of this project is to better understand how this protein is regulated that can highlight ways in which to alter the enzymes activity to modulate immune responces.

Funding Amount $AUD 511,294.64

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant