POSNOC (Positive Sentinel Node – a randomised trial of adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy) [ 2015 - 2020 ]

Research Grant

Researchers: Prof Gregory Mann (Principal investigator) ,  A/Pr Ian Campbell ,  A/Pr Nicholas Wilcken ,  Dr Christopher Pyke ,  Dr James Kollias
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Brief description POSNOC (POsitive Sentinel NOde – adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy) will address the key unresolved challenge in breast cancer surgery. A controversial US trial, ACOSOG Z0011, indicates that many breast cancer patients with limited disease in the sentinel node can safely avoid further nodal surgery. This would be a major advance, but there is widespread doubt that the results are broadly applicable. POSNOC will clarify this key issue.

Funding Amount $AUD 1,223,428.08

Funding Scheme Project Grants

Notes Standard Project Grant