Pneumococcal conjugate vaccine (PCV) schedules for the Northern Territory (NT): randomised controlled trial of booster vaccines to broaden and strengthen protection from invasive and mucosal infections. [ 2013 - 2017 ]

Research Grant

Researchers: Prof Amanda Leach (Principal investigator) ,  A/Pr Heidi Smith-Vaughan ,  A/Pr Mark Chatfield ,  Ms Anne Balloch ,  Prof Edward Mulholland
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Brief description Very few Indigenous children in remote communities have healthy ears or lungs; almost 20% have eardrum perforations. The associated hearing loss causes educational disadvantage with life long impacts on quality of life. New pneumococcal conjugate vaccines target a broader diversity of pathogens that cause eardrum perforation and lung infections, but the best schedules and combinations have not been tested. This randomised controlled trial will compare immune response, bacterial carriage and clinical outcomes of different vaccine schedules.

Funding Amount $AUD 2,078,861.58

Funding Scheme Project Grants

Notes Standard Project Grant