Platelet receptor shedding in stroke and thrombosis [ 2009 - 2011 ]

Research Grant

Researchers: A/Pr Elizabeth Gardiner (Principal investigator) ,  A/Pr Robert Andrews

Brief description In response to tissue injury and bleeding, blood platelets use receptors to form a thrombus (blood clot) and block further loss of blood and aid tissue repair. In inflammation or disease, abberant platelet activation can form a thrombus within cerebral (stroke) or coronary vessels (heart attack). We examine how a thrombus-limiting step (platelet receptor shedding) is triggered in thrombus-forming platelets, and if shed receptor can be used as a blood marker of abberant platelet activation.

Funding Amount $AUD 552,503.14

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant