Platelet receptor regulation in autoimmune disease [ 2010 - 2012 ]

Research Grant

Researchers: A/Pr Elizabeth Gardiner (Principal investigator) ,  A/Pr Robert Andrews

Brief description In response to bleeding, blood platelets use receptors to form a thrombus (blood clot) and block further loss of blood and aid tissue repair. People treated with heparin prior to surgery, can form autoantibodies that attack platelets, leading to thombus and thrombocytopenia (dangerous loss of circulating platelets). This is a significant clinical problem that is difficult to diagnose. We will determine how platelet receptor shedding can aid the diagnosis of heparin-induced thrombocytopenia.

Funding Amount $AUD 507,536.44

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant