A pilot study to evaluate the safety of intravenously administered human amnion epithelial cells in patients with compensated cirrhosis [ 2017 - 2019 ]

Research Grant

Researchers: Prof William Sievert (Principal investigator) ,  Dr Rebecca Lim

Brief description We propose a first-in-man clinical trial of human amnion epithelial cells (hAEC), a stem cell from the placenta, to assess safety in patients with stable liver cirrhosis. Worldwide, cirrhosis is the 6th most common cause of death. Liver transplantation remains the only chance for survival for some people with cirrhosis. In animal models, hAEC can substantially reduce liver scar tissue. Our goal is to develop hAEC as a therapy to reduce the need for liver transplantation.

Funding Amount $AUD 403,293.70

Funding Scheme Project Grants

Notes Standard Project Grant