Piezo2 and Pain - Is there a role for Piezo2 in mechanically induced bone pain? [ 2018 - ]

Research Grant

Researchers: A/Pr Jason Ivanusic (Principal investigator) ,  A/Pr Stuart Mazzone

Brief description Pain associated with bone marrow edema, osteoarthritis, bone cancer and fracture puts a significant burden on individuals, society, and the health care system in Australia. A dominant feature of these includes mechanical disturbances of the bone, and this is a trigger for the pain. In this study, we will determine if a newly discovered mechanically gated ion channel (Piezo2) is a key contributor to mechanically induced bone pain and could be a target for development of drugs to treat it.

Funding Amount $543,848.00

Funding Scheme Project Grants

Notes Standard Project Grant