Physiological consequences of the loss of inhibin activity [ 2015 - 2017 ]

Research Grant

Researchers: A/Pr Craig Harrison (Principal investigator) ,  A/Pr David Robertson ,  A/Pr Paul Gregorevic ,  Prof Matthew Gillespie

Brief description Inhibin A and B are essential factors in mammalian reproduction, negatively regulating pituitary production of follicle stimulating hormone (FSH). Interestingly, declines in inhibin levels at menopause correlate with a rapid decrease in bone and muscle mass. We propose that inhibin A and B have important physiological roles in the stimulation of bone and muscle growth, and that inhibins could be utilised to treat postmenopausal complications, including osteoporosis and sarcopenia.

Funding Amount $AUD 613,035.09

Funding Scheme Project Grants

Notes Standard Project Grant