grant

Physiological consequences of the loss of inhibin activity [ 2015 - 2017 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1078879]

Researchers: A/Pr Craig Harrison (Principal investigator) ,  A/Pr David Robertson A/Pr Paul Gregorevic Prof Matthew Gillespie

Brief description Inhibin A and B are essential factors in mammalian reproduction, negatively regulating pituitary production of follicle stimulating hormone (FSH). Interestingly, declines in inhibin levels at menopause correlate with a rapid decrease in bone and muscle mass. We propose that inhibin A and B have important physiological roles in the stimulation of bone and muscle growth, and that inhibins could be utilised to treat postmenopausal complications, including osteoporosis and sarcopenia.

Funding Amount $AUD 613,035.09

Funding Scheme Project Grants

Notes Standard Project Grant

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