Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1052494]Researchers: Prof Phillip Robinson (Principal investigator) , Dr Mark Graham
Brief description Antiepileptic drugs typically target ion transporters or neurotransmitter receptors. Synaptic vesicle glycoprotein 2 (SV2) is a rare example of a synaptic vesicle recycling protein that is the target of an antiepileptic drug. It also binds botulinum and tetanus neurotoxins. We discovered SV2 contains activity-dependent signalling molecules. Charactersation of these molecules and will allow a deeper understanding of the molecular basis for its role in epilepsy and toxin action.
Funding Amount $AUD 613,311.63
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1052494
- PURL : https://purl.org/au-research/grants/nhmrc/1052494