A phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of post-surgical bleeding.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1156641]

Brief description Cryopreservation extends platelet shelf-life from 5 days to 2 years. However, evidence is insufficient for widespread use. Our recent 121-patient pilot trial found encouraging results. We now propose an 808-patient definitive trial in bleeding surgical patients, measuring blood loss, transfusion requirement, complications, and cost. Even if cryopreserved platelets are only equivalent to liquid-stored platelets, their longer shelf-life would justify rapid change in clinical practice worldwide.

Funding Amount $1,825,648.00

Funding Scheme Project Grants

Notes Standard Project Grant

Subjects

Identifiers

nhmrc : GNT1156641
PURL : https://purl.org/au-research/grants/nhmrc/GNT1156641

A phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of post-surgical bleeding. [ 2019 - ]

Research Grant

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