A phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis [ 2012 - 2015 ]

Research Grant

Researchers: Prof Jeffrey Lipman (Principal investigator) ,  A/Pr Joshua Davis ,  Dr Joel Dulhunty ,  Prof Charles Gomersall ,  Prof Jason Roberts
View all 6 related researchers

Brief description This randomised controlled trial aims to compare, in critically-ill patients with severe sepsis managed in the intensive care unit, whether the administration of beta-lactam antibiotics via continuous infusion improves outcomes for patients compared with standard intermittent dosing. The potential significance of this step-wise research program is that it may lead to a simple and cost-effective intervention to improve ICU-free days, clinical cure and survival for patients with severe infections.

Funding Amount $AUD 947,371.74

Funding Scheme Project Grants

Notes Standard Project Grant