The pharmacology of sulfotransferase 4A1 [ 2016 - 2018 ]

Research Grant

Researchers: Prof Rodney Minchin (Principal investigator) ,  Dr Neville Butcher

Brief description SULT4A1 is not a sulfotransferase, but a sulfotransferase inhibitor. It forms high affinity heterodimers with other sulfotransferases via a conserved dimerisation site in its carboxyl terminus attenuating catalytic activity. Consequently, it is important for the metabolism of numerous important molecules including estrogens, thyroid hormones, neurotransmitters and many therapeutic agents.

Funding Amount $AUD 593,272.35

Funding Scheme Project Grants

Notes Standard Project Grant