Pharmacogenomics and mechanistic basis of drug hypersensitivity [ 2014 - 2017 ]

Research Grant

Researchers: Prof Elizabeth Phillips (Principal investigator) ,  A/Pr Lloyd D'Orsogna ,  A/Pr Michaela Lucas ,  E/Pr Ian James ,  Prof Simon Mallal

Brief description Drug allergy causes physical harm, anxiety and may limit treatment options. We introduced personalised genetic testing to prevent one such drug hypersensitivity. Genetic information from patients who have had adverse drug reactions will be used to work out how drugs trigger severe allergic reactions and develop strategies to predict these reactions and design safer drugs. This research has relevance to our understanding of other inflammatory disease such as autoimmune disease and multiple sclerosis.

Funding Amount $AUD 677,220.29

Funding Scheme Project Grants

Notes Standard Project Grant