Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/628611]Researchers: Prof Stephen Rogerson (Principal investigator) , A/Pr Anthony Jaworowski , Prof Kevin Kain
Brief description Macrophage white blood cells clear malaria infected cells by eating them, by three routes- by recognising ANTIBODIES or COMPLEMENT on the cell surface, or by the cell BINDING directly to the macrophage. Each has different results, such as amounts of cytokines produced. Cytokines clear malaria; in excess they can cause fatal immune pathology. We will investigate how variations in amount of antibody and complement and route of uptake of malaria infected cells might determine malaria outcome.
Funding Amount $AUD 564,644.09
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 628611
- PURL : https://purl.org/au-research/grants/nhmrc/628611
