grant

Peptide conjugates of splice-correcting oligonucleotides for enhanced in vitro and in vivo delivery for neuromuscular disease therapy. [ 2012 - 2016 ]

Also known as: Development of novel modified DNA-based therapy for neuromuscular diseases.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1034300]

Researchers: Dr Fazel Shabanpoor (Principal investigator)

Brief description Currently, there is no known cure for certain neuromuscular genetic disorders. However, recently identified synthetic DNA-type biomolecules have shown promising results in reversing such diseases in mice. These biomolecules cannot easily enter the cells in high enough quantity to elicit their beneficial effects. Therefore, this project will aim at identifying novel vecotrs that, when coupled to these biomolecules, are capable of delivering them into specific cell types as well as into the brain.

Funding Amount $AUD 332,347.91

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

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