Peptidase inhibitor 16: a new biomarker for human Treg [ 2011 - 2014 ]

Also known as: Identification and development of PI16 as a Treg cell surface marker

Research Grant

[Cite as]

Researchers: Prof Simon Barry (Principal investigator) ,  Dr Doreen Krumbiegel Prof Heddy Zola

Brief description As autoimmune diseases including type 1 diabetes and IBD are on the increase, there is still great need for novel diagnostic or therapeutic molecules. We have discovered a novel role for a protein called PI16, which we believe is a biomarker for natural regulatory T cells. These cells police the immune system, preventing inappropriate immune responses such as those that cause autoimmune diseases. This project will confirm its suitability for use as a diagnostic or therapeutic biomarker.

Funding Amount $AUD 391,262.03

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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