[Cite as http://purl.org/au-research/grants/nhmrc/1003185]
Prof Simon Barry
Dr Doreen Krumbiegel
Prof Heddy Zola
Brief description As autoimmune diseases including type 1 diabetes and IBD are on the increase, there is still great need for novel diagnostic or therapeutic molecules. We have discovered a novel role for a protein called PI16, which we believe is a biomarker for natural regulatory T cells. These cells police the immune system, preventing inappropriate immune responses such as those that cause autoimmune diseases. This project will confirm its suitability for use as a diagnostic or therapeutic biomarker.
Funding Amount $AUD 391,262.03
Funding Scheme NHMRC Project Grants
Standard Project Grant