Pathways that regulate nuclear export of circular RNA [ 1/1/2021 - 12/31/2024 ]

Research Grant

Brief description An emerging and unusual class of RNA molecules, circular RNAs (circRNAs), is widespread and plays important roles in cancer initiation and progression. However, the pathways responsible for nuclear export of circRNAs are unknown. We propose here to systematically determine how circRNAs are exported from the nucleus and characterise the effect of modulating circRNA export pathways in cancer. This will enable us to determine whether circRNAs can function as a biomarker of patient response.

Funding Amount $933,327

Funding Scheme Ideas Grants

Chief Investigator Dr Vihandha Wickramasinghe

Notes Ideas Grants