Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/546016]Researchers: Prof Leon Bach (Principal investigator) , Dr Ping Fu , Prof Greg Rice
Brief description Insulin-like growth factors (IGFs) are important proteins that regulate growth. When not regulated properly, diseases such as cancer can occur. A family of IGF binding proteins regulates IGFs. IGFBPs may inhibit IGFs and we have shown that one of them, IGFBP-6, decreases growth of some experimental cancers. As well as regulating IGFs, some IGFBPs alter cell behaviour independently of IGFs, and we found that IGFBP-6 stimulates cell movement in this way. We will now determine how this happens.
Funding Amount $AUD 550,724.99
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 546016
- PURL : https://purl.org/au-research/grants/nhmrc/546016