grant

Pathophysiology and treatment of pharyngo-oesophageal dysfunction [ 2000 - 2002 ]

Also known as: Mechanisms of regurgitation

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/113856]

Researchers: Prof Ian Cook (Principal investigator)

Brief description A number of oral and respiratory tract diseases such as laryngitis, asthma, unexplained cough, sinusitis, and obstructive sleep apnoea, have been linked with gastroesophageal reflux disease. These particular respiratory complications carry significant morbidity and mortality. The mechanisms of regurgitation of gastric acid, via the oesophagus into the pharynx, are unknown. We have recently validated a novel technique to reliably detect acid regurgitation events into the pharynx. We propose to use this technique, combined with pressure recordings from the oesophagus and its valves, to determine the precise mechanisms underlying acid regurgitation into the throat. Such studies should lead to better means of treating these disorders.

Funding Amount $AUD 168,275.44

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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