[Cite as http://purl.org/au-research/grants/nhmrc/508046]
Prof Cory Xian
A/Pr Bruce Foster
Brief description Childhood chemotherapy often causes growth arrest, osteoporosis, and fractures in cancer patients and survivors. Using a rat model, this project will study how the most commonly used chemotherapy drug methotrexate causes bone growth defects and examine any protective effects of two natural-derived substances. This work will increase our knowledge on chemotherapy-induced bone growth defects, and will be useful for developing a preventative treatment.
Funding Amount $AUD 622,598.08
Funding Scheme NHMRC Project Grants
Standard Project Grant