Pathophysiology and alternative preventative strategy for breast cancer chemotherapy-induced bone loss [ 2011 - 2013 ]

Research Grant

Researchers: Prof Cory Xian (Principal investigator) ,  Prof Peter Howe ,  Prof Ross Mckinnon

Brief description Combination cytotoxic chemotherapy is the current optimal approach for treating breast cancer in premenopausal women. However, long-term skeletal defects (osteoporosis and fractures) caused by the chemotherapy have become an increasingly serious problem due to its intensified use and improved patient survival rate. This project seeks to elucidate the mechanisms for chemotherapy-induced bone defects and to initiate development of a preventative treatment using natural bioactive micronutrients.

Funding Amount $AUD 540,356.57

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant