grant

Pathophysiological Mechanisms in the Antiphospholipid Syndrome: B2GPI Regulation of FXI-FXIa [ 2008 - 2010 ]

Also known as: Autoantibodies Inducing Thrombosis

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/510130]

Researchers: Prof Steven Krilis (Principal investigator)

Brief description The major protein that the antibodies in the antiphospholipid syndrome (APS) bind is called Beta 2-GPI. Antibodies to Beta 2-GPI are associated with recurrent miscarriage, intrauterine growth retardation, clots and stroke. Treatment of patients with the APS are treated with medication that has significant side effects. The development of more targeted and effective therapies for the APS requires a greater understanding of how the antibodies cause their effects, which is addressed in this study.

Funding Amount $AUD 530,591.62

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]
ACN 633 798 857