Pathogenic role of CDA1 via its profibrotic action in diabetic nephropathy [ 2008 - 2010 ]

Research Grant

Researchers: Prof Mark Cooper (Principal investigator) ,  Dr Zemin Cao ,  Dr Zhonglin Chai

Brief description We cloned a CDA1 several years ago and found that it played a major role in controlling a series of molecular events leading to production and accumulation of extracellular matrix causing scarring, as seen in diabetic nephropathy. This project aims to study the biological functions and molecular mechanisms of CDA1 in the context of diabetic nephropathy, hence allowing us to consider CDA1 as a molecular target for drug development to treat this condition and related complications.

Funding Amount $AUD 483,737.21

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant