Pathogenesis of Persistent Human Virus Infections of Global Significance [ 2005 - 2009 ]

Research Grant

Researchers: Prof Anthony Cunningham (Principal investigator) ,  A/Pr Barry Slobedman ,  Prof Bruce Brew ,  Prof Sharon Lewin ,  Prof Steven Wesselingh
View all 6 related researchers

Brief description The study will investigate why humans cannot eradicate particular viruses (HIV-AIDS, cytomegalovirus and herpes simplex virus), the long term effects of these viruses and ways to improve control. Current treatments can only partly suppress the levels of these viruses, because they persist in certain parts of the body called reservoirs, only to resurge later causing disease. Thus, the overall aim of the research program is to discover the mechanisms by which these viruses are able to successfully persist within reservoirs in the human body. The research program brings together a group of 6 leading scientists and clinicians located at 3 sites in 2 Australian cities. The team is comprised of experts in the study of HIV-AIDS, cytomegalovirus and herpes simplex virus who will combine their knowledge and expertise to speed up the process of research on these viruses that are of major health importance. Studies will also utilise a number of cutting edge technologies that now make it possible to much more rapidly and precisely determine how viruses cause disease. Advances in our understanding of how viruses persist may form the basis for treatments aimed at controlling persistent infections and the serious diseases caused by these viruses.

Funding Amount $AUD 6,571,328.38

Funding Scheme Programs

Notes Program Grant