Pathobiology that causes fatal thrombosis in HIT [ 2018 - ]

Research Grant

Researchers: A/Pr Elizabeth Gardiner (Principal investigator) ,  A/Pr Robert Andrews ,  Dr Adam Cuker ,  Prof Michael Berndt ,  Prof Phillip Hogarth
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Brief description Autoimmune-based thrombocytopenia can be a life-threatening adverse event associated with viral load, surgery, drug therapies or the use of the anticoagulant, heparin. This grant will define mechanisms of anti-platelet antibody-dependent platelet activation and assess shedding of platelet-specific glycoprotein (GP)VI as an immediate consequence of this activation, provide a new strategy for evaluating risk of thrombosis in HIT.

Funding Amount $398,371.00

Funding Scheme Project Grants

Notes Standard Project Grant