Pathobiology that causes fatal thrombosis in HIT [ 2018 - 2020 ]

Research Grant

Researchers: A/Pr Elizabeth Gardiner (Principal investigator) ,  A/Pr Robert Andrews ,  Prof Mark Hogarth ,  Prof Michael Berndt ,  Prof Ross Baker

Brief description Autoimmune-based thrombocytopenia can be a life-threatening adverse event associated with viral load, surgery, drug therapies or the use of the anticoagulant, heparin. This grant will define mechanisms of anti-platelet antibody-dependent platelet activation and assess shedding of platelet-specific glycoprotein (GP)VI as an immediate consequence of this activation, provide a new strategy for evaluating risk of thrombosis in HIT.

Funding Amount $AUD 403,948.20

Funding Scheme Project Grants

Notes Standard Project Grant