PACAP: The mechanism underlying sleep apnoea-induced hypertension [ 2014 - 2016 ]

Also known as: PACAP, sleep apnoea and high blood pressure

Research Grant

[Cite as]

Researchers: Prof Paul Pilowsky (Principal investigator) ,  Dr Melissa Farnham A/Pr Richard Wilson

Brief description 10% of Australians suffer from sleep apnoea; a cause of high blood pressure. Untreated, high blood pressure causes heart failure, kidney failure and stroke. A major cause of high blood pressure is an increased amount of nerve activity that controls the heart and blood vessels. In this proposal we will investigate how a brain chemical, called PACAP, affects nerve activity and blood pressure in a model of sleep apnoea. This information may lead to new and better treatments for high blood pressure.

Funding Amount $AUD 505,117.11

Funding Scheme Project Grants

Notes Standard Project Grant

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