grant

How do p75 and sortilin facilitate TrkA-mediated survival signalling? [ 2011 - 2013 ]

Also known as: How do neurotrophin receptors signal neuronal survival?

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1002610]

Researchers: Prof Elizabeth Coulson (Principal investigator) ,  Prof Anders Nykjær

Brief description Neurotrophins are the classical growth factors that regulate neuronal survival and death throughout the nervous system in both the developing and adult animal. These factors signal through one of three receptors, but precisely how the receptors interact to propagate cell survival is unclear. The goal of this grant is to unravel the molecular basis underpinning this life and death signalling decision so that we can then devise ways to promote cell survival in neurodegenerative conditions

Funding Amount $AUD 559,354.28

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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