Oxidative stress, heparan sulfates and endothelial dysfunction [ 2009 - 2012 ]

Research Grant

Researchers: A/Pr Shane Thomas (Principal investigator) ,  Dr Mark Hulett ,  Prof Anthony Kettle

Brief description During vascular disease endothelial cells that line the blood lumen are dysfunctional. Growing evidence indicates a role for a protein that the immune system normally uses to destroy infectious agents. This protein accumulates in diseased blood vessels next to endothelial cells. This project will study how this protein causes endothelial dysfunction and test the ability of novel agents to remove this protein from diseased blood vessels to improve endothelial function.

Funding Amount $AUD 450,390.69

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant