Optimising inhaled polymyxins as a vital therapy for pulmonary infections: A novel biochemical, molecular imaging and systems pharmacology approach [ 2016 - 2018 ]

Research Grant

Researchers: Prof Jian Li (Principal investigator) ,  Dr Fanfan Zhou ,  Dr Qi Zhou ,  Dr Tony Velkov ,  Prof Hak-Kim Chan

Brief description Lung infection is a leading cause of death in Australia and globally. Many bacterial pathogens are resistant to almost all current antibiotics. A class of ‘old’ antibiotics, polymyxins, are the last option for bacterial ‘superbugs’. Unfortunately, the current use of polymyxins is suboptimal and can cause severe kidney toxicity. This multi-disciplinary project will apply cutting-edge techniques to optimise inhaled polymyxin therapy for treatment of life-threatening pulmonary infections.

Funding Amount $AUD 749,189.09

Funding Scheme Project Grants

Notes Standard Project Grant