NY-ESO-1 expression as an inducible chemosensitivity marker [ 2013 - ]

Research Grant

Researchers: Dr Sem Liew (Principal investigator)

Brief description Immunotherapy is a new concept treatment for lung cancer. Cancer testis antigen (CTA, eg NY-ESO-1) is an immunogenic molecule that was related with poor outcomes, but our recent studies have found that tumours that express NY-ESO-1 are more responsive to chemotherapy. We are also able to induce expression of NY-ESO-1 in cells that do not normally express it using demethylating agents. We aim to determine if we can increase the response to chemotherapy by using these drugs in combination.

Funding Amount $113,237.00

Funding Scheme Postgraduate Scholarships

Notes Medical/Dental Postgraduate Scholarship