Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/606409]Researchers: Prof David Jans (Principal investigator) , Prof Ramesh Akkina
Brief description Our work indicates that the NS5 protein from Dengue virus (DV) has distinct sequences that enable it to traffic into and out of the host cell nucleus to exert pathogenic effects on transcription and thereby impair the host cell anti-viral and immune responses. We aim to characterise these properties in detail, and demonstrate their importance to DV pathogenicity using a novel animal model of the disease.
Funding Amount $AUD 736,953.57
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 606409
- PURL : https://purl.org/au-research/grants/nhmrc/606409
