Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1010098]Researchers: Prof Mark Cooper (Principal investigator) , Dr Zemin Cao , Dr Zhonglin Chai
Brief description Kidney fibrosis is a serious complication seen in diabetic subjects. This process is mainly controlled by transforming growth factor beta (TGF-beta). However, direct targeting of TGF-beta as a therapeutic approach is inappropriate due to its other important functions. Our preliminary data show that Cell Division Autoantigen 1 (CDA1) is critical for the disease causing activity of TGF-beta. We propose to use our recently generated unique CDA1 gene knockout mouse to demonstrate this important role of CDA1.
Funding Amount $AUD 578,351.99
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 1010098
- PURL : https://purl.org/au-research/grants/nhmrc/1010098
