Novel skeletal muscle enriched genes in muscle biology and disease [ 2018 - 2020 ]

Research Grant

Researchers: Prof Alistair Forrest (Principal investigator) ,  Dr Gianina Ravenscroft ,  Dr Robert Bryson-Richardson ,  Prof Nigel Laing

Brief description Each year hundreds of Australians are born with genetic muscle diseases, however, current methods fail to identify the causative disease gene in ~50% of patients. Here we will use expression patterns in skeletal muscle to prioritize novel candidate disease causing genes. We will functionally test the role of genes expressed in skeletal muscle cells using novel experimental assays. Uniquely, we will for the first time incorporate a novel class of gene (long non-coding RNAs) into our study.

Funding Amount $AUD 900,467.49

Funding Scheme Project Grants

Notes Standard Project Grant