grant

Novel role of innate immune DNA sensors in promoting gastric cancer [ 2018 - 2021 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1139371]

Researchers: Prof Brendan Jenkins (Principal investigator) ,  Prof Patrick Tan

Brief description Stomach cancer is the third most lethal cancer worldwide, and is strongly associated with inflammation (gastritis) caused by Helicobacter pylori bacterial infection. However it remains unknown how Helicobacter triggers gastritis and stomach cancer in people. Using a mouse model for gastritis-associated stomach cancer, our aim is to demonstrate the role of immune system proteins in the stomach which detect bacterial and host DNA to drive chronic inflammatory responses that lead to stomach cancer.

Funding Amount $AUD 784,861.34

Funding Scheme Project Grants

Notes Standard Project Grant

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