A novel role for CBF? as a regulator of breast cancer [ 2014 - 2017 ]

Research Grant

Researchers: A/Pr Matthew Naylor (Principal investigator) ,  Prof Christopher Ormandy

Brief description Whole genome sequencing studies of human breast tumours identified a handful of common significantly mutated genes, all previously linked to breast cancer, except one, CBF?. Preliminary data from our lab now show that CBF? may be a new regulator of human breast cancer and metastasis. Using mice with altered CBF? levels, breast cancer models and human patient cohorts, this study aims to identify a novel role for CBF? as a new regulator of human breast cancer and potential therapeutic target.

Funding Amount $AUD 682,415.70

Funding Scheme Project Grants

Notes Standard Project Grant