A novel role for Alzheimer tau protein in insulin secretion and type 2 diabetes [ 2017 - 2020 ]

Research Grant

Researchers: A/Pr Sofianos Andrikopoulos (Principal investigator) ,  Dr Peng Lei ,  Prof Ashley Bush

Brief description There is a strong association between type 2 diabetes and Alzheimer's disease, however the reason for this is not known. In Azheimer's disease a protein called tau does not function normally and contributes to the declining cognitive function. We have shown that when tau is absent, this lowers blood glucose and reduces the hallmark defects that contribute to type 2 diabetes. By understanding how tau works we may be able to provide better therapeutic agents to treat type 2 diabetes.

Funding Amount $AUD 1,048,180.39

Funding Scheme Project Grants

Notes Standard Project Grant